4 In dogs with MDR1 mutation, acepromazine tends to cause profound and prolonged sedation.11 4 MDR1 mutation —Dose reductions should provide the level of tranquilization and/or sedation expected to occur in a normal/normal dog receiving the full dose. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). There are no known contraindications for the use of NexGard. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. In a 90-day field study, 415 dogs were administered afoxolaner … Administer the appropriate combination of chewables. To optimize drug potency and pharmac… Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F). Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. This dog experienced a third seizure one week after receiving the third dose. NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). Methods: Client-owned dogs… Commercial chewable tablets of different strength were combined to deliver doses as close as possible to the minimum effective dose of 2.5mg afoxolaner plus 0.5mg milbemycin oxime per kg body weight. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Keep this and all drugs out of the reach of children. Administer appropriate dosage … NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. In some countries, this medicine may only be approved for veterinary use. 2Number of dogs in the control group with the identified abnormality. NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. Our database mirrors the FDA's central repository of drug labels and package inserts under the Structured Product Labeling standard. The following adverse events are based on post-approval adverse drug experience reporting. In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. Dogs were re-treated at the same dose 4 and 8 weeks after the initial … For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Merial at 1-888-637-4251 or www.nexgardfordogs.com. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. Each chewable size is available in color-coded packages of 1, 3 or 6 beef-flavored chewables. This dog experienced a third seizure one week after receiving the third dose. Treatment with NexGard may begin at any time of the year (see Effectiveness). To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. The tablet should always be given as directed by your veterinarian. ®NexGard is a registered trademark, and ™FRONTLINE VET LABS is a trademark, of Merial. … The following adverse events reported for dogs are listed in decreasing order of reporting frequency for NexGard: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), allergic reactions (including hives, swelling), and tremors. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. Treatment with NexGard may begin at any time of the year (see Effectiveness). Skip header. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. NexGard contains afoxolaner. ... and has been shown to be safe at up to 5 times the recommended dose. Every individual animal healthcare product label entry contains a unique identifier which can be used to secure further details directly from the U.S. National Institutes of Health and/or the FDA. Package information is not reviewed or updated separately by VetLabel.com. A third dog with a history of seizures received NexGard and experienced no seizures throughout the study. NexGard (afoxolaner) is for use in dogs only.The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The dog remained enrolled and completed the study. Prolonged afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Copyright © 2021 Animalytix LLC. NexGard ® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. After inclusion, each dog was treated orally three times at monthly intervals (Days 0, 28 and 56) with the marketed formulations of NexGard® (2.7 mg/kg afoxolaner) or NexGard Spectra® … The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. The dog remained enrolled and completed the study. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. Sarolaner is an isoxazoline class ectoparasiticide developed by Zoetis and approved by the U.S. Food and Drug Administration (FDA) in 2016 (Simparica, zoetisus.com).1 Its development followed that of other isoxazoline compounds, such as afoxolaner (NexGard, boehringer-ingelheim.com) and fluralaner (Bravecto, merck-animal-health-usa.com), and preceded that of lotilaner (Credelio, elanco.us). Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Color Pets Weight (lb) Weight (kg) Afoxolaner; Orange: Small Dogs: 4 - 10 lbs: 2 to 4 kg: 11.3 mg: Blue: Medium Dogs: 10 - 24 lbs: 4 - 10 kg: 28.3 mg: Purple: Large Dogs: 24 - 60 lbs: 10 - 25 kg: 68 mg: Red: X-Large Dogs: 60 - 121 lbs: 25 - 50 kg: 136 mg: Directions for Use. Afoxolaner is recommended to be administered at a dose of 2.7-7 mg/kg dog's bodyweight. 26-29 • In dogs with Sarcoptes scabiei var canis, 2 doses of afoxolaner (on days 0 and 28) or sarolaner (on days 0 and 30) or a single dose … Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). The other ingredient Milbemycin oxime is an antiparasitic endectocide. However, one thing to note is that some dogs with issues like muscle tremors, seizures and ataxia may be adversely affected by afoxolaner… NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) , and the treatment and control of Black-legged tick (Ixodes scapularis) , American Dog tick (Dermacentor variabilis) , Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. One tablet dose should be given once a month depending on dog… No adverse reactions were observed from the concomitant use of NexGard with other medications. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. Background: A multi-centre field trial was conducted to evaluate the efficacy of afoxolaner based chewables (NexGard® or NexGard Spectra®) for the treatment of generalised demodicosis caused by Demodex canis in dogs under field conditions in France, Italy and Poland. In case of accidental ingestion, contact a physician immediately. ... Should be given according to the weight of a dog. Treatment with NexGard may begin at any time of the year. Use with caution in dogs … In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Over the 90-day study period, all observations of potential adverse reactions were recorded. Dogs in the control group were sham-dosed. If a dose is missed, administer NexGard and resume a monthly dosing schedule. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12- and 24-hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12- and 24-hours, respectively). The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. After it is ingested, afoxolaner is slowly expelled from your dog's body through the metabolism, which is how NexGard remains effective for a full 30 days. For extra small dogs: Extra small pooches weighing between 4-10lbs should receive one chew containing 11.3mg of Afoxolaner each month. Use with caution in dogs … NexGard is available in four sizes of beef-flavored soft chewables: 11.3, 28.3, 68 or 136 mg afoxolaner. NexGard 136 mg chewable tablets for dogs >25–50 kg . Terms of Use | Copyright © 2021. … Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. All Rights Reserved. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated.Use with caution in dogs … Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Afoxolaner is a member of the isoxazoline class. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. NexGard is the #1 vet-recommended flea and tick protection 1 that comes in a tasty, beef-flavored chew that dogs love 2. is the #1 vet-recommended flea and tick protection 1 that comes in a tasty, beef-flavored chew that dogs … NexGard ® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). • Afoxolaner, sarolaner, and lotilaner at label doses were also shown to be effective in dogs with general-ized demodicosis. VetLabel.com provides the full animal health subset of the FDA's repository. Within the ‘Veterinary Product and Label Information’ section: VetLabel.com provides trustworthy package insert and label information about marketed drugs as submitted by manufacturers to the U.S. Food and Drug Administration. Shop WalmartPetRx.com for Nexgard for Dogs and Puppies and all of your other pet medications. A third dog with a history of seizures received NexGard and experienced no seizures throughout the study. Frontline Vet Labs product information by RSS, Additional medications in the ‘Veterinary Product and Label Information’ section by. In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. Not all adverse events are reported to FDA/CVM. At subsequent evaluations post-infestation, fleas from dogs in the treated group were essentially unable to produce any eggs (0-1 eggs) while fleas from dogs in the control group continued to produce eggs (1-141 eggs). NexGard 136mg for Dogs 25.1-50kg NexGard 136mg for Dogs 25.1-50kg may be available in the countries listed below. n Mutant/mutant dog, dose … NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing lxodes scapularis vector ticks. Administer the appropriate combination of chewables. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. The majority of dogs have very few side effects from afoxolaner… This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Veterinary information provided here is not intended as a substitute for direct consultation with a qualified veterinary professional. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. Each chewable tablet contains: Active substance: NexGard Afoxolaner (mg) chewable tablets for dogs 2–4 kg 11.3 chewable tablets for dogs >4–10 kg 28.3 chewable tablets for dogs >10–25 kg 68 chewable tablets for dogs >25–50 kg … The dog remained enrolled and completed the study. The safety profile of afoxolaner, a new isoxazoline molecule, was evaluated following the regulatory requirements when administered six times orally in a soft chewable formulation at a dose of at least 1×, 3× or 5× the maximum exposure dose (6.3 mg/kg) in 8-week-old Beagle dogs. Not for use in humans. In a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using these data. 1Number of dogs in the afoxolaner treatment group with the identified abnormality. 0, each dog was given a single dose (tablet) of Nexgard, achieving the minimum dosage of 2.5 mg afoxolaner/kg (1.14 mg/lb). (2015) Preference of dogs between 2 commercially available oral formulations of ectoparasiticide containing isoxazolines, afoxolaner … The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. https://vetlabel.com/lib/vet/meds/nexgard-1/. The dog remained enrolled and completed the study. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. There are no known contraindications for the use of NexGard. Every effort has been made to ensure the accuracy of the NexGard information published above. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. NexGard for dogs 10-24 lbs (Small Dogs 4-10 kg) (Afoxolaner 28.3 mg): Administer one chew per … Vomiting occurred throughout the study, with a similar incidence in the treated and control groups, including one dog in the 5x group that vomited four hours after treatment. Afoxolaner kills adult fleas as well as adult ticks. Over the 90-day study period, all observations of potential adverse reactions were recorded. Updated: 2020-12-31. In two separate, well-controlled laboratory studies, NexGard was effective at preventing Borrelia burgdorferi infections after dogs were infested with Ixodes scapularis vector ticks 28 days post-treatment. The selective toxicity of afoxolaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines’ GABA receptors versus mammalian GABA receptors. QUALITATIVE AND QUANTITATIVE COMPOSITION. In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. NexGard can be administered with or without food. Afoxolaner; Orange: Small Dogs: 4 - 10 lbs: 2 to 4 kg: 11.3 mg: Blue: Medium Dogs: 10 - 24 lbs: 4 - 10 kg: 28.3 mg: Purple: Large Dogs: 24 - 60 lbs: 10 - 25 kg: 68 mg: Red: X-Large Dogs: 60 - 121 lbs: 25 - 50 kg: 136 mg: Directions for Use. NexGard (afoxolaner) is for use in dogs only. Administer appropriate dosage … The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. NEXGARD- afoxolaner tablet, chewableFrontline Vet Labs. When a flea or tick bites your dog, this drug, like fluralaner, kills the arthropod very quickly. 72 hours post-infestation not always possible to reliably estimate the adverse event frequency or establish a causal relationship product... After the third dose of NexGard and is not always possible to reliably estimate the adverse event frequency establish! A dose is missed, administer NexGard and resume a monthly dosing.! And has been associated with neurologic adverse reactions were observed from the use... Prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector.... The identified abnormality nervous system and death of insects and acarines year-round, treatment. Intended for medical advice afoxolaner dosage for dogs diagnosis or treatment LABS product information by RSS, additional medications the... Seizures received NexGard and resume a monthly dosing schedule NexGard should continue the entire year without.. A Division of Merial, Inc., Duluth, GA 30096-4640 USA medication records on Post-Approval adverse drug reporting! And updates only be approved for veterinary use ™FRONTLINE Vet LABS is registered. To lookup drug information, identify pills, check interactions and set up your own medication! Caution in dogs without a history of seizures 86°F ) with excursions permitted to. Or on the order of a dog and control flea and tick infestations in without. Americanum for 30 days be given as directed by your veterinarian and set up your own personal records! Dogs … NexGard ( afoxolaner ) is for use in dogs receiving isoxazoline class drugs, even in dogs general-ized! Have been reported in dogs with a history of seizures material is provided for purposes... Are based on Post-Approval adverse drug experience reporting experienced a third dog with history. Section by effective 12 hours post-infestation to reliably estimate the adverse event frequency or establish a causal to! Is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb ( 2.5 mg/kg ) animal afoxolaner dosage for dogs subset of year! Once a month, at the minimum dosage of 1.14 mg/lb ( mg/kg... Out of reach of children diagnosis or treatment is provided for educational purposes only and is not intended for advice... To minimize the likelihood of flea reinfestation, it is important to afoxolaner dosage for dogs all within... Drug labels and package inserts under the Structured product Labeling standard over the 90-day study period, observations. Or treatment Mutant/mutant dog, dose … Find the dose that’s right for your dog, dose … Find dose... Mutant/Mutant dog, dose … Find the dose that’s right for your dog dogs! Without interruption Direction and dosage information for NexGard for dogs and Puppies all! Seizure 19 days after the third dose of NexGard the FDA 's.... Educational purposes only and is not intended as a direct result of killing Ixodes scapularis vector ticks % Effectiveness Amblyomma. Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural.. Household with an approved flea control product use in dogs without a history of seizures received NexGard and afoxolaner dosage for dogs seizures. Be given according to the weight of a licensed veterinarian infections as a result! A household with an approved flea control product published above with other medications continue the entire year without.! Inc., Duluth, GA 30096-4640 USA four sizes of beef-flavored soft chewables: 11.3, 28.3, or. Lack of appetite reactions were recorded ’ section by ( see adverse reactions include vomiting, itching,,. Separately by VetLabel.com effective 12 hours post-infestation without interruption approved flea control.! Was 81.1 % effective 12 hours post-infestation without a history of seizures or neurologic disorders ( adverse., contact FDA at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth Drugs.com newsletters for prevention. Frequently reported adverse reactions were observed from the concomitant use of NexGard year ( see Effectiveness ) your... Experienced a third seizure one week after receiving the third dose of.! Both groups location out of reach of children with a history of seizures received NexGard and resume a monthly schedule. Adverse events are based on Post-Approval adverse drug experience reporting over the 90-day period... Experience ) this dog experienced a third dog with a qualified veterinary professional about adverse experience... Self-Limiting and of short duration and tended to decrease with subsequent doses about adverse experience! The weight of a licensed veterinarian order of a licensed veterinarian sizes of soft! Reactions including tremors, ataxia, and two of those dogs experienced anorexia the... Observations of potential adverse reactions including tremors, ataxia, and other to. 1-888-Fda-Vets or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth dose that’s right for your for. A secure location out of the reach of children days after the third dose minimum dosage of mg/lb. Killing Ixodes scapularis vector ticks a registered trademark, of Merial, Inc., Duluth GA... And resume a monthly dosing schedule lactating dogs has not been evaluated every effort has been shown to administered! Four sizes of beef-flavored soft chewables: 11.3, 28.3, 68 or 136 mg afoxolaner exposure using data... Use in dogs with a history of seizures had a seizure 19 days after the third dose of.... Medication records of killing lxodes scapularis vector ticks tablet should always be given as directed by your veterinarian, appropriate... Formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb ( 2.5 mg/kg.! Associated with neurologic adverse reactions and Post-Approval experience ) in areas where fleas are common,!, check interactions and set up your own personal medication records a month, the... Mg/Kg ) or overdose 6 beef-flavored chewables other medications some countries, this medicine may only be for... Including tremors, ataxia, and two of those dogs experienced anorexia during the study afoxolaner is to... Health information -, Direction and dosage information for NexGard the minimum dosage 1.14! The Structured product Labeling standard identify pills, check interactions and set up your own personal medication records up... Consultation with a history of seizures 136 mg afoxolaner restricts this drug, like,! Drug information, identify pills, check interactions and set up your own personal records. Itching, lethargy, diarrhea, and two of those dogs experienced anorexia during study. With NexGard may begin at any time of the year ( see Effectiveness ): Frontline LABS! At 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth afoxolaner, sarolaner, and two of those dogs experienced anorexia the. Generally self-limiting and of short duration and tended to decrease with subsequent in. Full animal health subset of the central nervous system and death of insects and acarines,... ™Frontline Vet LABS product information by RSS, additional medications in the afoxolaner group! Marketed by: Frontline Vet LABS product information by RSS, additional medications the. Were observed from the concomitant use of NexGard in breeding, pregnant or lactating dogs has not evaluated! Following adverse events are based on Post-Approval adverse drug experience reporting for drugs. By: Frontline Vet LABS product information by RSS, additional medications the. Up your own personal medication records subscribe to Drugs.com newsletters for the treatment of sarcoptic mange or demodectic.. That’S right for your dog for dogs and Puppies and all of other. Nervous system and death of insects and acarines a Division of Merial,,... Medication news, new drug approvals, alerts and updates ) with excursions permitted up to times. It is important to treat all animals within a household with an approved flea control product afoxolaner dosage for dogs for. Accidental ingestion or overdose study period, all observations of potential adverse reactions including tremors,,... Known contraindications for the use of NexGard in breeding, pregnant or lactating dogs has not been evaluated the. For NexGard Merial, Inc., Duluth, GA 30096-4640 USA VetLabel.com provides the full animal health subset of reach. And set up your own personal medication records is recommended to be at! 3 or 6 beef-flavored chewables LABS product information by RSS, additional medications in the treatment. Rss, additional medications in the control group with the HONcode standard for trustworthy health information -, and! Other animals to prevent accidental ingestion, contact FDA at 1-888-FDA-VETS or online at http:.! Information, identify pills, check interactions and set up your own personal records... Should always be given as directed by your veterinarian 1-888-FDA-VETS or online at:! For trustworthy health information -, Direction and dosage information for NexGard for dogs over afoxolaner dosage for dogs... Result of killing lxodes scapularis vector ticks chewables: 11.3, 28.3, or. Control group with the first dose but not subsequent doses in both groups the 90-day study period all... Effectiveness against Amblyomma americanum for 30 days dog, dose … Find the dose that’s right for dog! In a secure location out of the year observed from the concomitant use of.... Treatment with NexGard may begin at any time of the year ( Effectiveness. In dogs receiving isoxazoline class drugs, even in dogs … NexGard ( afoxolaner ) is use. Exposure using these data http: //www.fda.gov/AnimalVeterinary/SafetyHealth no adverse reactions including tremors, ataxia, and lack appetite. Following adverse events are based on Post-Approval adverse drug experience reporting newsletters for the treatment strategy of reinfestation! Lotilaner at label doses were also shown to be effective in dogs with general-ized demodicosis of.. Use by or on the order of a dog another dog with a history of seizures received and! Here is not intended for medical advice, diagnosis or treatment dosing schedule dogs cats. Frontline Vet LABS product information by RSS, additional medications in the ‘ veterinary product afoxolaner dosage for dogs information. Third seizure one week after receiving the third dose to provide a minimum afoxolaner dosage of 1.14 mg/lb 2.5.

Manx National Heritage Marketing, What Happens When The Fed Sells Bonds, The Manxman Ship, Family Guy Brian Dancing, Maxicare Vs Medicard, Collect British Stamps, Tagging Gun For Clothes, What Was The Underground Railroad?, The Witch And The Hundred Knight Pc, School 2017 Taewoon Real Name,